effect of superparamagnetic iron oxide nanoparticles-labeling on mouse embryonic stem cells
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Effect of Superparamagnetic Iron Oxide Nanoparticles-Labeling on Mouse Embryonic Stem Cells
OBJECTIVE Superparamagnetic iron oxide nanoparticles (SPIONs) have been used to label mammalian cells and to monitor their fate in vivo using magnetic resonance imaging (MRI). However, the effectiveness of phenotype of labeled cells by SPIONs is still a matter of question. The aim of this study was to investigate the efficiency and biological effects of labeled mouse embryonic stem cells (mESCs...
متن کاملCytotoxic Effect of Iron Oxide Nanoparticles on Mouse Embryonic Stem Cells by MTT Assay
Background: Despite the wide range of applications, there is a serious lack of information on the impact of the nanoparticles on human health and the environment. The present study was done to determine the range of dangerous concentrations of iron oxide nanoparticle and their effects on mouse embryonic stem cells. Methods: Iron oxide nanoparticles with less than 20 nanometers diameter were en...
متن کاملcytotoxic effect of iron oxide nanoparticles on mouse embryonic stem cells by mtt assay
background: despite the wide range of applications, there is a serious lack of information on the impact of the nanoparticles on human health and the environment. the present study was done to determine the range of dangerous concentrations of iron oxide nanoparticle and their effects on mouse embryonic stem cells. methods: iron oxide nanoparticles with less than 20 nanometers diameter were enc...
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متن کاملCytotoxic Effect of Iron Oxide Nanoparticles on Mouse Embryonic Stem Cells by MTT Assay
1. Department of Biological Sciences, Kharazmi University, Tehran, Iran. 2. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. 3. MSc student in Developmental Biology Sciences, Kharazmi University, Tehran, Iran. 4. BSc in Biology, Reproductive Biomedicine Research Center, Royan Institute fo...
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Targeted delivery of cells and therapeutic agents would benefit a wide range of biomedical applications by concentrating the therapeutic effect at the target site while minimizing deleterious effects to off-target sites. Magnetic cell targeting is an efficient, safe, and straightforward delivery technique. Superparamagnetic iron oxide nanoparticles (SPION) are biodegradable, biocompatible, and ...
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عنوان ژورنال:
cell journalجلد ۱۷، شماره ۲، صفحات ۲۲۱-۲۳۰
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